Proteinuria in nephrotic syndrome treatments

If you have proteinuria in nephrotic syndrome and are looking for a treatment, ask your doctor about your options.

It’s always good to talk to your doctor openly and honestly about your condition. That can help both of you to work together and find a treatment that’s right for you.

Developing a Treatment Plan That Works for You

Talking about treatments with your doctor may get a little confusing at times. This section will try to break this information down into easy-to-understand terms.

To start with, your doctor may prescribe more than one type of treatment for you. For example, one part of your treatment plan may work to reduce your proteinuria. Meanwhile, another part of your plan may treat the condition that caused your nephrotic syndrome in the first place. And lastly, other treatments may be given to help manage other medical conditions related to nephrotic syndrome.

Keep in mind, the below material is provided to begin to help inform you. This is not meant to be a complete list of treatments. Only you and your doctor can work together to choose a treatment plan that may be right for you.

The doctor-patient relationship

Working closely with her doctors gives Nicole the strength to face her condition head-on and with confidence.

Treatments for Nephrotic Syndrome

The following types of medications may be prescribed to treat nephrotic syndrome:

  • Steroids and immunosuppressant agents
    A steroid (also called a corticosteroid) and other medicines that block the immune system from attacking healthy tissue are used to treat certain kidney conditions. These drugs also help to control inflammation.
  • Alkylating agents
    Some treatments used to treat cancer may also be used to treat nephrotic syndrome.
  • Other treatment options
    There are other treatment options, including one that works with your body to help treat proteinuria in nephrotic syndrome.

Treatments for Other Medical Conditions Related to Nephrotic Syndrome

Having nephrotic syndrome may lead to other medical problems. These may include high blood pressure, swelling, an increased risk of infection, and others. The following are some of the types of medications that may be used to help treat and manage these conditions:

  • Blood pressure medications—Drugs to help reduce and control high blood pressure (hypertension)
  • High cholesterol medicines (statins)—Treatments to help reduce high cholesterol levels
  • Water pills (diuretics)—Drugs to help control the swelling caused by fluid buildup in your body
  • Blood thinners (anticoagulants)—Treatments to help lessen the risk of blood clots
  • Pneumococcal vaccine and yearly flu shots—These may help protect you against bacterial infection
Understand your kidney condition

Joe was frustrated by his symptoms—but relieved to finally learn what was wrong.

Treatments for Nephrotic Syndrome as a Complication of Another Condition

In some cases, nephrotic syndrome may be a complication of another disorder, such as:

  • Diabetes
  • Hepatitis B or C
  • HIV, and others 

Your doctor may recommend additional treatments not mentioned here for these and other related medical conditions.

The above is not a complete list of treatments. Always talk with your healthcare team about your own specific medical condition and the type of treatments you may require.

Maintaining a Healthy Diet and Lifestyle

Along with medical treatments, a healthy diet and lifestyle may also help you manage your condition. This includes a diet that’s low in salt, protein, and saturated fats and cholesterol. Regular exercise and not smoking may help as well.

Remember: Always talk to your doctor before making a change in your diet or starting a new exercise routine.


Mallinckrodt intends this website to be informative, but you should remember the contents are general in nature and not meant to substitute for specific advice from healthcare professionals that may be necessary based on your individual questions and needs. We have made reasonable efforts to provide helpful and accurate information, however we make no guarantees and you should not solely rely on the information included here.

Know your kidneys.

Along with filtering waste from your blood, your kidneys also help create red blood cells, control blood pressure, and help manage your body’s fluid level.

Finding the right treatment

Remember, everyone responds to treatment differently. What’s important is partnering with your doctor to find a treatment plan that works for you.

To help you start the conversation and make the most of your next appointment, download a Doctor Discussion Guide and a Lab Results Tracker now.

Know your numbers

Encouraged by his wife, Joe keeps on top of his lab tests and explains his results.

Ask your healthcare provider about what therapy can help you reduce protein levels in your urine.